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Long survival in a 69,XXX triploid infant in Greece
Dimitrios Iliopoulos1, Georgia Vassiliou2, Eleni Sekerli2, Vasiliki Sidiropoulou2,
Alexandra Tsiga2, Despina Dimopoulou2 and Nikolaos Voyiatzis2
1School of Medicine, Ohio State University, Columbus, OH, USA
2Laboratory of Cytogenetics, 2nd Department of Pediatrics, A.H.E.P.A. Hospital,
School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Corresponding author: D. Iliopoulos
E-mail: dimiliopou@yahoo.com
Genet. Mol. Res. 4 (4): 755-759 (2005)
Received June 27, 2005
Accepted October 14, 2005
Published December 12, 2005

ABSTRACT. The live birth of a triploidy infant is a very rare event and death usually occurs within the first hours of life. Triploid cases with a survival of more than two months are infrequent. We report on an infant with a 69,XXX chromosome constitution who survived 164 days. Chromosomal analysis demonstrated a 69,XXX karyotype with no evidence of mosaicism. This is the longest survival reported for this condition to date in Greece and the fourth longest worldwide. The infant was admitted to our clinic several times due to respiratory problems, and supplementary oxygen was required. The improved survival of our case was possibly due to better management of respiratory illness and prematurity, and these are essential factors that physicians should consider carefully with such rare cases.

Key words: Triploidy, 69,XXX, Long survival

 

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