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Support vector machines for novel class detection in Bioinformatics
Eduardo J. Spinosa and André C.P.L.F. de Carvalho
Instituto de Ciências Matemáticas e de Computação, Universidade de São Paulo,
São Carlos, SP, Brasil
Corresponding author: E.J. Spinosa
E-mail: ejspin@icmc.usp.br/ejspin@yahoo.com
Genet. Mol. Res. 4 (3): 608-615 (2005)
Received May 20, 2005
Accepted July 8, 2005
Published September 30, 2005

ABSTRACT. Novelty detection techniques might be a promising way of dealing with high-dimensional classification problems in Bioinformatics. We present preliminary results of the use of a one-class support vector machine approach to detect novel classes in two Bioinformatics databases. The results are compatible with theory and inspire further investigation.

Key words: Novelty detection, Support vector machines, Bioinformatics, Gene expression analysis, Machine learning

 

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