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- Mutual information content of homologous DNA sequences
- Helena Cristina G. Leitão1, Luciana S. Pessôa1 and Jorge Stolfi2
- 1Instituto de Computação, Universidade Federal Fluminense (UFF), Niterói, RJ, Brasil
- 2Instituto de Computação, Universidade Estadual de Campinas (UNICAMP), Niterói, RJ, Brasil
- Corresponding author: H.C.G. Leitão
- E-mail: hcgl@ic.uff.br
- Genet. Mol. Res. 4 (3): 553-562 (2005)
- Received May 20, 2005
- Accepted July 8, 2005
- Published September 30, 2005
ABSTRACT. The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DNA sequence that can be useful to identify sequences homologous to it. To reach it, we used signal processing techniques, specially spectral analysis and information theory.
Key words: DNA sequence analysis, Homologous DNA sequences, Information theory, Fourier analysis
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