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Mutual information content of homologous DNA sequences
Helena Cristina G. Leitão1, Luciana S. Pessôa1 and Jorge Stolfi2
1Instituto de Computação, Universidade Federal Fluminense (UFF), Niterói, RJ, Brasil
2Instituto de Computação, Universidade Estadual de Campinas (UNICAMP), Niterói, RJ, Brasil
Corresponding author: H.C.G. Leitão
E-mail: hcgl@ic.uff.br
Genet. Mol. Res. 4 (3): 553-562 (2005)
Received May 20, 2005
Accepted July 8, 2005
Published September 30, 2005

ABSTRACT. The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DNA sequence that can be useful to identify sequences homologous to it. To reach it, we used signal processing techniques, specially spectral analysis and information theory.

Key words: DNA sequence analysis, Homologous DNA sequences, Information theory, Fourier analysis

 

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