Allele frequencies and their standard errors were calculated from the genotypes of individuals for the two strata and the total population (Table 1). The allele distributions at each
ACKNOWLEDGMENTS
We thank Bruce Budowle for unselfish help with the statistics analysis, Ana Gladys Rivas for efficient laboratory work, and Lafayette Eaton for correcting the English and reviewing the genetic analyses. Ranjit Chakraborty made valuable comments on an earlier draft of the paper. Research supported by Fondecyt Project No. 1960405.
REFERENCES
Acuña, M., Jorquera, H., Armanet, L. and Cifuentes, L. (2000). Gene frequencies for four hypervariable DNA loci in a Chilean population of mixed ancestry. J. Forensic Sci. 45: 1160-1161.
Bernstein, F. (1931). Die geographische Verteilung der Blutgruppen und ihre anthropologische Bedentung. In: Comitato Italiano per lo Studio dei Problemi Della Populazione. Instituto Poligrafico dello Stato, Rome, 227.
Budowle, B., Baechtel, F.S., Smerick, J.B., Presley, K.W., Giusti, A.M., Parsons, G., Alevy, M.C. and Chakraborty, R. (1995). D1S80 population data in African Americans, Caucasians, Southeastern Hispanics, Southwestern Hispanics, and Orientals. J. Forensic Sci. 40: 38-44.
Campillo, FL. (1976). Estudio de los grupos sanguíneos en la población Española. Comunicación de la Real Academia de Medicina. Tomo XCII de los Anales, Cuaderno tercero, Madrid.
Chakraborty, R., Smouse, P.E. and Neel, J.V. (1988). Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of Central and South America. Am. J. Hum. Genet. 43: 709-725.
Chakraborty, R., Fornage, M., Guegue, R. and Boerwinkle, E. (1991). Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population. In: DNA Fingerprinting: Approaches and Applications (Burke, T., Dolf, G., Jeffreys, A.J. and Wolff, R., eds.). Birkhauser Verlag, Berlin, pp. 127-143.
Chakraborty, R., Srinivasan, M.R. and Andrade, M. (1993). Intraclass and interclass correlations of allele sizes within and between loci in DNA typing data. Genetics 133: 411-419.
Comey, C.T., Koons, B.W., Presley, K.W., Smerick, J.V., Sobieralski, C.A., Stanley, D.M. and Baechtel, F.S. (1994). DNA extraction strategies for amplified fragment length polymorphism analysis. J. Forensic Sci. 39: 1254-1269.
Edwards, A., Hammond, H.A., Jin, L., Caskey, C.T. and Chakraborty, R. (1992). Genetic variation at five trimeric and tetrameric repeat loci in four human population groups. Genomics 12: 241-253.
Guo, S.W. and Thompson, E.A. (1992). Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 48: 361-372.
Huckenbeck, W., Kuntze, K. and Scheil, H.G. (Eds.) (1997). The Distribution of the Human DNA-PCR Polymorphisms. Verlag Dr. Köster, Berlin, Germany, pp. 173-196.
Jorquera, H. and Budowle, B. (1998). Chilean population data on ten PCR based loci. J. Forensic Sci. 43: 171-173.
Karlin, S., Cameron, E.C. and Williams, P.T. (1981). Sibling and parent-offspring correlation estimation with variable family size. Proc. Natl. Acad. Sci. USA 78: 2664-2668.
Kasai, K., Nakamura, Y. and White, R. (1990). Amplification of a variable number of tandem repeat (VNTR) locus (pMCT118) by the polymerase chain reaction (PCR) and its application to forensic science. J. Forensic Sci. 35: 1196-1200.
Li, C.C. (1976). First Course in Population Genetics. Boxwood Press, Pacific Grove, CA, USA.
Llop, E. and Rothhammer, F. (1988). A note on presence of blood groups A and B in pre-Colombian South America. Am. J. Phys. Anthropol. 75: 107-111.
Matson, G.A., Sutton, H.E., Etcheverry, R., Swanson, J. and Robinson, A. (1967). Distribution of hereditary blood groups among Indians in South America IV. In Chile. Am. J. Phys. Anthropol. 27: 157-194.
Nei, M. (1978). Estimation of average heterozygosity and genetic distance from a small number of individuals. Genetics 89: 583-590.
Nei, M. and Roychoudhury, A.K. (1974). Sampling variances of heterozygosity and genetic distance. Genetics 76: 379-390.
Sepúlveda, O. (1960). Clasificación nacional jerarquizada de las ocupaciones expresadas en grandes estratos (ms). Facultad de Sociología, Universidad de Chile, Santiago, Chile.
Valenzuela, Y.C. (1988). On sociogenetic clines. Ethol. Sociobiol. 9: 259-268.
Valenzuela, Y.C., Acuña, M. and Harb, Z. (1987). Gradiente sociogenético en la población Chilena. Rev. Méd. Chile 115: 295-299.
Weiner, A. (1968). Chances of proving non-paternity with a system determined by triple allelic co-dominant genes. Am. J. Hum. Genet. 20: 279-282.
Weir, B.S. (1992). Independence of VNTR alleles defined by fixed bins. Genetics 130: 873-887.
Zago, M.A., Silva, W.A., Tavella, M.H., Santos, S.E.B., Guerreiro, J.F. and Figueiredo, M.S. (1996). Interpopulational and intrapopulational genetic diversity of Amerindians as revealed by six variable number of tandem repeats. Hum. Hered. 46: 274-289.